Herpes Simplex Virus 1 (HSV-1) ICP22 Protein Directly Interacts with Cyclin-Dependent Kinase (CDK)9 to Inhibit RNA Polymerase II Transcription Elongation

The Herpes Simplex Virus 1 (HSV-1)-encoded ICP22 protein plays an important role in viral infection and affects expression of host cell genes. ICP22 is known to reduce the global level of serine (Ser)2 phosphorylation of the Tyr1Ser2Pro3Thr4Ser5Pro6Ser7 heptapeptide repeats comprising the carboxy-te...

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Detalles Bibliográficos
Autores principales: Zaborowska, Justyna, Baumli, Sonja, Laitem, Clelia, O'Reilly, Dawn, Thomas, Peter H., O'Hare, Peter, Murphy, Shona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169428/
https://www.ncbi.nlm.nih.gov/pubmed/25233083
http://dx.doi.org/10.1371/journal.pone.0107654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169428/
https://www.ncbi.nlm.nih.gov/pubmed/25233083
http://dx.doi.org/10.1371/journal.pone.0107654

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