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Ocular Localization and Transduction by Adenoviral Vectors Are Serotype-Dependent and Can Be Modified by Inclusion of RGD Fiber Modifications

PURPOSE: To evaluate localization and transgene expression from adenoviral vector of serotypes 5, 35, and 28, ± an RGD motif in the fiber following intravitreal or subretinal administration. METHODS: Ocular transduction by adenoviral vector serotypes ± RGD was studied in the eyes of mice receiving a...

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Detalles Bibliográficos
Autores principales:	Ueyama, Kazuhiro, Mori, Keisuke, Shoji, Takuhei, Omata, Hidekazu, Gehlbach, Peter L., Brough, Douglas E., Wei, Lisa L., Yoneya, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169476/ https://www.ncbi.nlm.nih.gov/pubmed/25232844 http://dx.doi.org/10.1371/journal.pone.0108071

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