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Crimean-Congo Hemorrhagic Fever Virus Entry into Host Cells Occurs through the Multivesicular Body and Requires ESCRT Regulators

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne bunyavirus causing outbreaks of severe disease in humans, with a fatality rate approaching 30%. There are no widely accepted therapeutics available to prevent or treat the disease. CCHFV enters host cells through clathrin-mediated endocyt...

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Detalles Bibliográficos
Autores principales: Shtanko, Olena, Nikitina, Raisa A., Altuntas, Cengiz Z., Chepurnov, Alexander A., Davey, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169490/
https://www.ncbi.nlm.nih.gov/pubmed/25233119
http://dx.doi.org/10.1371/journal.ppat.1004390