Lack of Prion Accumulation in Lymphoid Tissues of PRNP ARQ/ARR Sheep Intracranially Inoculated with the Agent of Scrapie

Sheep scrapie is a transmissible spongiform encephalopathy that can be transmitted horizontally. The prion protein gene (PRNP) profoundly influences the susceptibility of sheep to the scrapie agent and the tissue levels and distribution of PrP(Sc) in affected sheep. The purpose of this study was to...

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Detalles Bibliográficos
Autores principales: Greenlee, Justin J., Kunkle, Robert A., Richt, Jürgen A., Nicholson, Eric M., Hamir, Amir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169493/
https://www.ncbi.nlm.nih.gov/pubmed/25233232
http://dx.doi.org/10.1371/journal.pone.0108029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169493/
https://www.ncbi.nlm.nih.gov/pubmed/25233232
http://dx.doi.org/10.1371/journal.pone.0108029

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