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MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major

Although it is generally believed that CD4(+) T cells play important roles in anti-Leishmania immunity, some studies suggest that they may be dispensable, and that MHC II-restricted CD3(+)CD4(−)CD8(−) (double negative, DN) T cells may be more important in regulating primary anti-Leishmania immunity....

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Detalles Bibliográficos
Autores principales: Mou, Zhirong, Liu, Dong, Okwor, Ifeoma, Jia, Ping, Orihara, Kanami, Uzonna, Jude Ezeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169504/
https://www.ncbi.nlm.nih.gov/pubmed/25233487
http://dx.doi.org/10.1371/journal.ppat.1004396