Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes

Recent work on the use of mRNA lipoplexes for gene delivery demonstrates the need for a mathematical model that simulates and predicts kinetics and transfection efficiency. The small copy numbers involved make it necessary to use stochastic models and include statistical analysis of the variation ob...

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Detalles Bibliográficos
Autores principales: Ligon, Thomas S., Leonhardt, Carolin, Rädler, Joachim O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169511/
https://www.ncbi.nlm.nih.gov/pubmed/25237886
http://dx.doi.org/10.1371/journal.pone.0107148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169511/
https://www.ncbi.nlm.nih.gov/pubmed/25237886
http://dx.doi.org/10.1371/journal.pone.0107148

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