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Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT

OBJECTIVE: Interaction of stromal and tumor cells plays a dynamic role in initiating and enhancing carcinogenesis. In this study, we investigated the crosstalk between colorectal cancer (CRC) cells with stromal fibroblasts and the anti-cancer effects of curcumin and 5-Fluorouracil (5-FU), especially...

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Detalles Bibliográficos
Autores principales: Buhrmann, Constanze, Kraehe, Patricia, Lueders, Cora, Shayan, Parviz, Goel, Ajay, Shakibaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169561/
https://www.ncbi.nlm.nih.gov/pubmed/25238234
http://dx.doi.org/10.1371/journal.pone.0107514