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Proteolytic Activity of Prostate-Specific Antigen (PSA) towards Protein Substrates and Effect of Peptides Stimulating PSA Activity

Prostate-specific antigen (PSA or kallikrein-related peptidase-3, KLK3) exerts chymotrypsin-like proteolytic activity. The main biological function of PSA is the liquefaction of the clot formed after ejaculation by cleavage of semenogelins I and II in seminal fluid. PSA also cleaves several other su...

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Detalles Bibliográficos
Autores principales: Mattsson, Johanna M., Ravela, Suvi, Hekim, Can, Jonsson, Magnus, Malm, Johan, Närvänen, Ale, Stenman, Ulf-Håkan, Koistinen, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169579/
https://www.ncbi.nlm.nih.gov/pubmed/25237904
http://dx.doi.org/10.1371/journal.pone.0107819