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HBx Inhibits CYP2E1 Gene Expression via Downregulating HNF4α in Human Hepatoma Cells
CYP2E1, one of the cytochrome P450 mixed-function oxidases located predominantly in liver, plays a key role in metabolism of xenobiotics including ethanol and procarcinogens. Recently, down-expression of CYP2E1 was found in hepatocellular carcinoma (HCC) with the majority to be chronic hepatitis B v...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169590/ https://www.ncbi.nlm.nih.gov/pubmed/25238230 http://dx.doi.org/10.1371/journal.pone.0107913 |