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Plasticity versus specificity in RTK signalling modalities for distinct biological outcomes in motor neurons

BACKGROUND: Multiple growth factors are known to control several aspects of neuronal biology, consecutively acting as morphogens to diversify neuronal fates, as guidance cues for axonal growth, and as modulators of survival or death to regulate neuronal numbers. The multiplicity of neuronal types is...

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Detalles Bibliográficos
Autores principales: Caruso, Nathalie, Herberth, Balazs, Lamballe, Fabienne, Arce-Gorvel, Vilma, Maina, Flavio, Helmbacher, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169644/
https://www.ncbi.nlm.nih.gov/pubmed/25124859
http://dx.doi.org/10.1186/s12915-014-0056-6