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Importance of formalin fixing conditions for HER2 testing in gastric cancer: immunohistochemical staining and fluorescence in situ hybridization

BACKGROUND: Accurate and reliable assessment of human epidermal growth factor receptor type 2 (HER2) status is important for selecting patients with gastric cancer who may benefit from trastuzumab treatment. Here we examined the impact of formalin fixing conditions on HER2 immunohistochemistry (IHC)...

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Detalles Bibliográficos
Autores principales: Yamashita-Kashima, Yoriko, Shu, Sei, Yorozu, Keigo, Hashizume, Kaoru, Moriya, Yoichiro, Fujimoto-Ouchi, Kaori, Harada, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169649/
https://www.ncbi.nlm.nih.gov/pubmed/24414131
http://dx.doi.org/10.1007/s10120-013-0329-8