Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

Di-(2-ethylhexyl)-phthalate (DEHP) is a ubiquitously used endocrine disruptor.There is widespread exposure to DEHP in the general population which has raised substantial public concern due to its potential detrimental health effects. It is particularly pertinent to investigate the molecular mechanis...

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Detalles Bibliográficos
Autores principales: Li, Xiaolin, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Cui, Honghua, Qiu, Lu, Li, Jian, He, Yuping, Huang, Jing, Bohr, Vilhelm A., Ng, Tzi Bun, Guo, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170195/
https://www.ncbi.nlm.nih.gov/pubmed/25242624
http://dx.doi.org/10.1038/srep06434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170195/
https://www.ncbi.nlm.nih.gov/pubmed/25242624
http://dx.doi.org/10.1038/srep06434

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