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Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies

Turner syndrome is caused by complete or partial loss of the second sex chromosome and is characterized by spontaneous fetal loss in >90% of conceptions. Survivors possess an array of somatic and germline clinical characteristics. Induced pluripotent stem cells (iPSCs) offer an opportunity for in...

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Detalles Bibliográficos
Autores principales: Dominguez, Antonia A., Chiang, H. Rosaria, Sukhwani, Meena, Orwig, Kyle E., Reijo Pera, Renee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170197/
https://www.ncbi.nlm.nih.gov/pubmed/25242416
http://dx.doi.org/10.1038/srep06432