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Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies
Turner syndrome is caused by complete or partial loss of the second sex chromosome and is characterized by spontaneous fetal loss in >90% of conceptions. Survivors possess an array of somatic and germline clinical characteristics. Induced pluripotent stem cells (iPSCs) offer an opportunity for in...
Autores principales: | Dominguez, Antonia A., Chiang, H. Rosaria, Sukhwani, Meena, Orwig, Kyle E., Reijo Pera, Renee A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170197/ https://www.ncbi.nlm.nih.gov/pubmed/25242416 http://dx.doi.org/10.1038/srep06432 |
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