WT1 Interacts with MAD2 and Regulates Mitotic Checkpoint Function

Tumor suppressors safeguard the fidelity of the mitotic checkpoint by transcriptional regulation of genes that encode components of the mitotic checkpoint complex (MCC). Here we report a new role for the tumor suppressor and transcription factor, WT1, in the mitotic checkpoint. We show that WT1 regu...

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Detalles Bibliográficos
Autores principales: Shandilya, Jayasha, Toska, Eneda, Richard, Derek J, Medler, Kathryn F, Roberts, Stefan GE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170573/
https://www.ncbi.nlm.nih.gov/pubmed/25232865
http://dx.doi.org/10.1038/ncomms5903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170573/
https://www.ncbi.nlm.nih.gov/pubmed/25232865
http://dx.doi.org/10.1038/ncomms5903

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