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Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells

Gastric epithelial cell malignant transformation induced by Helicobactor Pylori contributes to tumor development, but the underlying mechanisms for this remain unclear. Here we demonstrate that RBP2, a newly identified histone demethylase, can be induced by CagA via PI3K/AKT-Sp1 pathway depending on...

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Detalles Bibliográficos
Autores principales: Liang, Xiuming, Zeng, Jiping, Wang, Lixiang, Shen, Li, Li, Shuyan, Ma, Lin, Ci, Xinyu, Yu, Jingya, Jia, Mutian, Sun, Yundong, Liu, Zhifang, Liu, Shili, Li, Wenjuan, Yu, Han, Chen, Chunyan, Jia, Jihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170602/
https://www.ncbi.nlm.nih.gov/pubmed/25015565