A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin

Accumulation of genetic and epigenetic changes contributes to cancer development and progression. Compared with gene mutations or deletions, epigenetic changes are reversible, which alter the chromatin structure remodeling instead of changes in DNA sequence, and therefore become a promising strategy...

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Detalles Bibliográficos
Autores principales: Wang, Li-Ting, Liou, Jing-Ping, Li, Yu-Hsuan, Liu, Yi-Min, Pan, Shiow-Lin, Teng, Che-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170623/
https://www.ncbi.nlm.nih.gov/pubmed/25015091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170623/
https://www.ncbi.nlm.nih.gov/pubmed/25015091

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