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The Ribosome Uses Two Active Mechanisms to Unwind mRNA During Translation

The ribosome translates the genetic information encoded in messenger RNA into protein. Folded structures in the coding region of an mRNA represent a kinetic barrier that slows the peptide elongation rate, as the ribosome must disrupt structures it encounters in the mRNA at its entry site to enable t...

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Detalles Bibliográficos
Autores principales: Qu, Xiaohui, Wen, Jin-Der, Lancaster, Laura, Noller, Harry F., Bustamante, Carlos, Tinoco, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170678/
https://www.ncbi.nlm.nih.gov/pubmed/21734708
http://dx.doi.org/10.1038/nature10126