High Content Imaging and Analysis Enable Quantitative In Situ Assessment of CYP3A4 Using Cryopreserved Differentiated HepaRG Cells

High-throughput imaging-based hepatotoxicity studies capable of analyzing individual cells in situ hold enormous promise for drug safety testing but are frequently limited by a lack of sufficient metabolically competent human cells. This study examined cryopreserved HepaRG cells, a human liver cell...

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Detalles Bibliográficos
Autores principales: Ranade, Aarati R., Wilson, Melinda S., McClanahan, Amy M., Ball, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170746/
https://www.ncbi.nlm.nih.gov/pubmed/25276124
http://dx.doi.org/10.1155/2014/291054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170746/
https://www.ncbi.nlm.nih.gov/pubmed/25276124
http://dx.doi.org/10.1155/2014/291054

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