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Silencing of Plasma Membrane Ca(2+)-ATPase Isoforms 2 and 3 Impairs Energy Metabolism in Differentiating PC12 Cells

A close link between Ca(2+), ATP level, and neurogenesis is apparent; however, the molecular mechanisms of this relationship have not been completely elucidated. Transient elevations of cytosolic Ca(2+) may boost ATP synthesis, but ATP is also consumed by ion pumps to maintain a low Ca(2+) in cytoso...

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Detalles Bibliográficos
Autores principales: Boczek, Tomasz, Lisek, Malwina, Ferenc, Bozena, Kowalski, Antoni, Wiktorska, Magdalena, Zylinska, Ludmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170788/
https://www.ncbi.nlm.nih.gov/pubmed/25276815
http://dx.doi.org/10.1155/2014/735106