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The Adaptor Protein Swiprosin-1/EFhd2 Is Dispensable for Platelet Function in Mice

BACKGROUND: Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity, but may also cause pathological vessel occlusion. Reorganizations of the platelet cytoskeleton and agonist-induced intracellular Ca(2+)-mobilization are crucial for platelet h...

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Detalles Bibliográficos
Autores principales: Morowski, Martina, Brachs, Sebastian, Mielenz, Dirk, Nieswandt, Bernhard, Dütting, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170979/
https://www.ncbi.nlm.nih.gov/pubmed/25243606
http://dx.doi.org/10.1371/journal.pone.0107139