The novel EpCAM-targeting monoclonal antibody 3–17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines

The epithelial cell adhesion molecule (EpCAM) is expressed by a wide range of human carcinomas, making it an attractive diagnostic and therapeutic target in oncology. Its recent identification on cancer stem cells has raised further interest in its use for tumor targeting and therapy. Here, we prese...

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Detalles Bibliográficos
Autores principales: Lund, Kaja, Bostad, Monica, Skarpen, Ellen, Braunagel, Michael, Kiprijanov, Sergej, Krauss, Stefan, Duncan, Alex, Høgset, Anders, Selbo, Pål K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171007/
https://www.ncbi.nlm.nih.gov/pubmed/24525727
http://dx.doi.org/10.4161/mabs.28207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171007/
https://www.ncbi.nlm.nih.gov/pubmed/24525727
http://dx.doi.org/10.4161/mabs.28207

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