Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies

Modification of antibody class and binding properties typically requires cloning of antibody genes, antibody library construction, phage or yeast display and recombinant antibody expression. Here, we describe an alternative “cloning-free” approach to generate antibodies with altered antigen-binding...

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Detalles Bibliográficos
Autores principales: Su, Yu-Cheng, Al-Qaisi, Talal S, Tung, Hsin-Yi, Cheng, Tian-Lu, Chuang, Kuo-Hsiang, Chen, Bing-Mae, Roffler, Steve R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171010/
https://www.ncbi.nlm.nih.gov/pubmed/24874693
http://dx.doi.org/10.4161/mabs.29124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171010/
https://www.ncbi.nlm.nih.gov/pubmed/24874693
http://dx.doi.org/10.4161/mabs.29124

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