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Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that plays an important role in the regulation of serum low-density lipoprotein (LDL) cholesterol by downregulation of LDL receptor, and as such is considered a novel target in cholesterol lowering therapy. In support of the...

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Detalles Bibliográficos
Autores principales: Colbert, Alexander, Umble-Romero, Amber, Prokop, Samantha, Xu, Ren, Gibbs, John P, Pederson, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171013/
https://www.ncbi.nlm.nih.gov/pubmed/24859266
http://dx.doi.org/10.4161/mabs.28719