Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC: overview and applications

Hydrophobic interaction chromatography-high performance liquid chromatography (HIC-HPLC) is a powerful analytical method used for the separation of molecular variants of therapeutic proteins. The method has been employed for monitoring various post-translational modifications, including proteolytic...

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Detalles Bibliográficos
Autores principales: Haverick, Mark, Mengisen, Selina, Shameem, Mohammed, Ambrogelly, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171020/
https://www.ncbi.nlm.nih.gov/pubmed/24751784
http://dx.doi.org/10.4161/mabs.28693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171020/
https://www.ncbi.nlm.nih.gov/pubmed/24751784
http://dx.doi.org/10.4161/mabs.28693

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