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Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC: overview and applications
Hydrophobic interaction chromatography-high performance liquid chromatography (HIC-HPLC) is a powerful analytical method used for the separation of molecular variants of therapeutic proteins. The method has been employed for monitoring various post-translational modifications, including proteolytic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171020/ https://www.ncbi.nlm.nih.gov/pubmed/24751784 http://dx.doi.org/10.4161/mabs.28693 |