Evaluation of cardiovascular parameters in cynomolgus monkeys following IV administration of LBR-101, a monoclonal antibody against calcitonin gene-related peptide

Calcitonin gene-related peptide (CGRP) is a well-validated target for migraine therapy and a known potent systemic vasodilator. LBR-101 is a monoclonal antibody against CGRP in clinical development for the preventive treatment of episodic and chronic migraine. Understanding the hemodynamic and cardi...

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Detalles Bibliográficos
Autores principales: Walter, Sarah, Alibhoy, Abbas, Escandon, Rafael, Bigal, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171022/
https://www.ncbi.nlm.nih.gov/pubmed/24866108
http://dx.doi.org/10.4161/mabs.29242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171022/
https://www.ncbi.nlm.nih.gov/pubmed/24866108
http://dx.doi.org/10.4161/mabs.29242

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