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Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility

Small non-coding RNAs act as critical regulators of gene expression and are essential for male germ cell development and spermatogenesis. Previously, we showed that germ cell-specific inactivation of Dicer1, an endonuclease essential for the biogenesis of micro-RNAs (miRNAs) and endogenous small int...

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Detalles Bibliográficos
Autores principales: Zimmermann, Céline, Romero, Yannick, Warnefors, Maria, Bilican, Adem, Borel, Christelle, Smith, Lee B., Kotaja, Noora, Kaessmann, Henrik, Nef, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171096/
https://www.ncbi.nlm.nih.gov/pubmed/25244517
http://dx.doi.org/10.1371/journal.pone.0107023