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FGF23 Deficiency Leads to Mixed Hearing Loss and Middle Ear Malformation in Mice

Fibroblast growth factor 23 (FGF23) is a circulating hormone important in phosphate homeostasis. Abnormal serum levels of FGF23 result in systemic pathologies in humans and mice, including renal phosphate wasting diseases and hyperphosphatemia. We sought to uncover the role FGF23 plays in the audito...

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Detalles Bibliográficos
Autores principales: Lysaght, Andrew C., Yuan, Quan, Fan, Yi, Kalwani, Neil, Caruso, Paul, Cunnane, MaryBeth, Lanske, Beate, Stanković, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171482/
https://www.ncbi.nlm.nih.gov/pubmed/25243481
http://dx.doi.org/10.1371/journal.pone.0107681