Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity

Interleukin 1 Receptor antagonist (IL-1Ra) is highly elevated in obesity and is widely recognized as an anti-inflammatory cytokine. While the anti-inflammatory role of IL-1Ra in the pancreas is well established, the role of IL-1Ra in other insulin target tissues and the contribution of systemic IL-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Franck, Niclas, Maris, Michael, Nalbandian, Sarah, Talukdar, Saswata, Schenk, Simon, Hofmann, Hans-Peter, Bullough, David, Osborn, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171490/
https://www.ncbi.nlm.nih.gov/pubmed/25244011
http://dx.doi.org/10.1371/journal.pone.0107487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171490/
https://www.ncbi.nlm.nih.gov/pubmed/25244011
http://dx.doi.org/10.1371/journal.pone.0107487

Ejemplares similares