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Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity

Interleukin 1 Receptor antagonist (IL-1Ra) is highly elevated in obesity and is widely recognized as an anti-inflammatory cytokine. While the anti-inflammatory role of IL-1Ra in the pancreas is well established, the role of IL-1Ra in other insulin target tissues and the contribution of systemic IL-1...

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Detalles Bibliográficos
Autores principales:	Franck, Niclas, Maris, Michael, Nalbandian, Sarah, Talukdar, Saswata, Schenk, Simon, Hofmann, Hans-Peter, Bullough, David, Osborn, Olivia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171490/ https://www.ncbi.nlm.nih.gov/pubmed/25244011 http://dx.doi.org/10.1371/journal.pone.0107487

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