A Sensitive, Reproducible and Objective Immunofluorescence Analysis Method of Dystrophin in Individual Fibers in Samples from Patients with Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is characterized by the absence or reduced levels of dystrophin expression on the inner surface of the sarcolemmal membrane of muscle fibers. Clinical development of therapeutic approaches aiming to increase dystrophin levels requires sensitive and reproducible meas...

Descripción completa

Detalles Bibliográficos
Autores principales: Beekman, Chantal, Sipkens, Jessica A., Testerink, Janwillem, Giannakopoulos, Stavros, Kreuger, Dyonne, van Deutekom, Judith C., Campion, Giles V., de Kimpe, Sjef J., Lourbakos, Afrodite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171506/
https://www.ncbi.nlm.nih.gov/pubmed/25244123
http://dx.doi.org/10.1371/journal.pone.0107494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171506/
https://www.ncbi.nlm.nih.gov/pubmed/25244123
http://dx.doi.org/10.1371/journal.pone.0107494

Ejemplares similares