Runx2-I Isoform Contributes to Fetal Bone Formation Even in the Absence of Specific N-Terminal Amino Acids

The Runt-related transcription factor 2 (Runx2) gene encodes the transcription factor Runx2, which is the master regulator of osteoblast development; insufficiency of this protein causes disorders of bone development such as cleidocranial dysplasia. Runx2 has two isoforms, Runx2-II and Runx2-I, and...

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Detalles Bibliográficos
Autores principales: Okura, Hideaki, Sato, Shintaro, Kishikawa, Sari, Kaneto, Satoshi, Nakashima, Tomoki, Yoshida, Nobuaki, Takayanagi, Hiroshi, Kiyono, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171521/
https://www.ncbi.nlm.nih.gov/pubmed/25244033
http://dx.doi.org/10.1371/journal.pone.0108294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171521/
https://www.ncbi.nlm.nih.gov/pubmed/25244033
http://dx.doi.org/10.1371/journal.pone.0108294

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