(99m)Tc Pyrene Derivative Complex Causes Double-Strand Breaks in dsDNA Mainly through Cluster-Mediated Indirect Effect in Aqueous Solution

Radiation therapy for cancer patients works by ionizing damage to nuclear DNA, primarily by creating double-strand breaks (DSB). A major shortcoming of traditional radiation therapy is the set of side effect associated with its long-range interaction with nearby tissues. Low-energy Auger electrons h...

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Detalles Bibliográficos
Autores principales: Chung, Wei-Ju, Cui, Yujia, Huang, Feng-Yun J., Tu, Tzu-Hui, Yang, Tzu-Sen, Lo, Jem-Mau, Chiang, Chi-Shiun, Hsu, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171534/
https://www.ncbi.nlm.nih.gov/pubmed/25244160
http://dx.doi.org/10.1371/journal.pone.0108162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171534/
https://www.ncbi.nlm.nih.gov/pubmed/25244160
http://dx.doi.org/10.1371/journal.pone.0108162

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