Podocyte Injury Caused by Indoxyl Sulfate, a Uremic Toxin and Aryl-Hydrocarbon Receptor Ligand

Indoxyl sulfate is a uremic toxin and a ligand of the aryl-hydrocarbon receptor (AhR), a transcriptional regulator. Elevated serum indoxyl sulfate levels may contribute to progressive kidney disease and associated vascular disease. We asked whether indoxyl sulfate injures podocytes in vivo and in vi...

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Detalles Bibliográficos
Autores principales: Ichii, Osamu, Otsuka-Kanazawa, Saori, Nakamura, Teppei, Ueno, Masaaki, Kon, Yasuhiro, Chen, Weiping, Rosenberg, Avi Z., Kopp, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171541/
https://www.ncbi.nlm.nih.gov/pubmed/25244654
http://dx.doi.org/10.1371/journal.pone.0108448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171541/
https://www.ncbi.nlm.nih.gov/pubmed/25244654
http://dx.doi.org/10.1371/journal.pone.0108448

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