Epigenetic regulation of spinal cord gene expression controls Opioid-Induced Hyperalgesia

BACKGROUND: The long term use of opioids for the treatment of pain leads to a group of maladaptations which includes opioid-induced hyperalgesia (OIH). OIH typically resolves within few days after cessation of morphine treatment in mice but is prolonged for weeks if histone deacetylase (HDAC) activi...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, De-Yong, Sun, Yuan, Shi, Xiao-You, Sahbaie, Peyman, Clark, J David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171542/
https://www.ncbi.nlm.nih.gov/pubmed/25217253
http://dx.doi.org/10.1186/1744-8069-10-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171542/
https://www.ncbi.nlm.nih.gov/pubmed/25217253
http://dx.doi.org/10.1186/1744-8069-10-59

Ejemplares similares