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Acquisition of radioresistance in docetaxel-resistant human lung adenocarcinoma cells is linked with dysregulation of miR-451/c-Myc-survivin/rad-51 signaling

Chemoresistant tumors usually fail to respond to radiotherapy. However, the mechanisms involved in chemo- and radiotherapy cross resistance are not fully understood. Previously, we have identified microRNA (miR)-451 as a tumor suppressor in lung adenocarcinoma (LAD). However, whether miR-451 plays c...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Chen, Dong-Qin, Huang, Jia-Yuan, Zhang, Kai, Feng, Bing, Pan, Ban-Zhou, Chen, Jing, De, Wei, Chen, Long-Bang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171617/
https://www.ncbi.nlm.nih.gov/pubmed/25026294