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The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells

Velcade is one of the inescapable drug to treat patient suffering from multiple myeloma (MM) and resistance to this drug represents a major drawback for patients. However, the mechanisms underlying velcade resistance remain incompletely understood. We derived several U266 MM cell clones that resist...

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Detalles Bibliográficos
Autores principales: Hamouda, Mohamed-Amine, Belhacene, Nathalie, Puissant, Alexandre, Colosetti, Pascal, Robert, Guillaume, Jacquel, Arnaud, Mari, Bernard, Auberger, Patrick, Luciano, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171627/
https://www.ncbi.nlm.nih.gov/pubmed/25051369