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Targeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematopoietic malignancy characterized by dismal prognosis and overall poor therapeutic response. Since the biology of BPDCN is barely understood, our study aims to shed light on the genetic make-up of these highly malignant tumors. Usi...

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Detalles Bibliográficos
Autores principales: Stenzinger, Albrecht, Endris, Volker, Pfarr, Nicole, Andrulis, Mindaugas, Jöhrens, Korinna, Klauschen, Frederick, Siebolts, Udo, Wolf, Thomas, Koch, Philipp-Sebastian, Schulz, Miriam, Hartschuh, Wolfgang, Goerdt, Sergij, Lennerz, Jochen K., Wickenhauser, Claudia, Klapper, Wolfram, Anagnostopoulos, Ioannis, Weichert, Wilko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171639/
https://www.ncbi.nlm.nih.gov/pubmed/25115387