Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice

This study investigated the impact of catalase (Cat) overexpression in renal proximal tubule cells (RPTCs) on nuclear factor erythroid 2–related factor 2 (Nrf2) stimulation of angiotensinogen (Agt) gene expression and the development of hypertension and renal injury in diabetic Akita transgenic mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdo, Shaaban, Shi, Yixuan, Otoukesh, Abouzar, Ghosh, Anindya, Lo, Chao-Sheng, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao Ling, Chan, John S.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171660/
https://www.ncbi.nlm.nih.gov/pubmed/24812425
http://dx.doi.org/10.2337/db13-1830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171660/
https://www.ncbi.nlm.nih.gov/pubmed/24812425
http://dx.doi.org/10.2337/db13-1830

Ejemplares similares