Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages

Group A Streptococcus (GAS, Streptococcus pyogenes) is an ongoing threat to human health as the agent of streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as necrotizing fasciitis and streptococcal toxic shock syndrome. In animal models of infection, ma...

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Detalles Bibliográficos
Autores principales: Bastiat-Sempe, Benedicte, Love, John F., Lomayesva, Natalie, Wessels, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172074/
https://www.ncbi.nlm.nih.gov/pubmed/25227466
http://dx.doi.org/10.1128/mBio.01690-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172074/
https://www.ncbi.nlm.nih.gov/pubmed/25227466
http://dx.doi.org/10.1128/mBio.01690-14

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