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Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages
Group A Streptococcus (GAS, Streptococcus pyogenes) is an ongoing threat to human health as the agent of streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as necrotizing fasciitis and streptococcal toxic shock syndrome. In animal models of infection, ma...
Autores principales: | Bastiat-Sempe, Benedicte, Love, John F., Lomayesva, Natalie, Wessels, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172074/ https://www.ncbi.nlm.nih.gov/pubmed/25227466 http://dx.doi.org/10.1128/mBio.01690-14 |
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