Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders

In the present study, we have investigated the functional profile of CD4 T cells from patients with common variable immunodeficiency (CVID), including production of cytokines and proliferation in response to bacteria and virus-derived antigens. We show that the functional impairment of CD4 T cells,...

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Detalles Bibliográficos
Autores principales: Perreau, Matthieu, Vigano, Selena, Bellanger, Florence, Pellaton, Céline, Buss, Guillaume, Comte, Denis, Roger, Thierry, Lacabaratz, Christine, Bart, Pierre-Alexandre, Levy, Yves, Pantaleo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172212/
https://www.ncbi.nlm.nih.gov/pubmed/25225461
http://dx.doi.org/10.1084/jem.20140039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172212/
https://www.ncbi.nlm.nih.gov/pubmed/25225461
http://dx.doi.org/10.1084/jem.20140039

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