Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

It is widely appreciated that effective human vaccines directed against viral pathogens elicit neutralizing antibodies (NAbs). The passive transfer of anti–HIV-1 NAbs conferring sterilizing immunity to macaques has been used to determine the plasma neutralization titers, which must be present at the...

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Detalles Bibliográficos
Autores principales: Shingai, Masashi, Donau, Olivia K., Plishka, Ronald J., Buckler-White, Alicia, Mascola, John R., Nabel, Gary J., Nason, Martha C., Montefiori, David, Moldt, Brian, Poignard, Pascal, Diskin, Ron, Bjorkman, Pamela J., Eckhaus, Michael A., Klein, Florian, Mouquet, Hugo, Cetrulo Lorenzi, Julio Cesar, Gazumyan, Anna, Burton, Dennis R., Nussenzweig, Michel C., Martin, Malcolm A., Nishimura, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172223/
https://www.ncbi.nlm.nih.gov/pubmed/25155019
http://dx.doi.org/10.1084/jem.20132494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172223/
https://www.ncbi.nlm.nih.gov/pubmed/25155019
http://dx.doi.org/10.1084/jem.20132494

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