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Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

Germinal centers (GCs) are the sites where memory B cells and plasma cells producing high-affinity antibodies are generated during T cell–dependent immune responses. The molecular control of GC B cell maintenance and differentiation remains incompletely understood. Activation of the NF-κB signaling...

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Detalles Bibliográficos
Autores principales: Heise, Nicole, De Silva, Nilushi S., Silva, Kathryn, Carette, Amanda, Simonetti, Giorgia, Pasparakis, Manolis, Klein, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172226/
https://www.ncbi.nlm.nih.gov/pubmed/25180063
http://dx.doi.org/10.1084/jem.20132613