Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs

Allogeneic hematopoietic stem cell (HSC) transplantation (HSCT) is currently the leading strategy to manage acute myeloid leukemia (AML). However, treatment-related morbidity limits the patient generalizability of HSCT use, and the survival of leukemic stem cells (LSCs) within protective areas of th...

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Detalles Bibliográficos
Autores principales: Boyd, Allison L., Campbell, Clinton J.V., Hopkins, Claudia I., Fiebig-Comyn, Aline, Russell, Jennifer, Ulemek, Jelena, Foley, Ronan, Leber, Brian, Xenocostas, Anargyros, Collins, Tony J., Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172227/
https://www.ncbi.nlm.nih.gov/pubmed/25180064
http://dx.doi.org/10.1084/jem.20140131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172227/
https://www.ncbi.nlm.nih.gov/pubmed/25180064
http://dx.doi.org/10.1084/jem.20140131

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