Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

Plasmacytoid dendritic cells (pDCs) have long been implicated in the pathogenesis of lupus. However, this conclusion has been largely based on a correlative link between the copious production of IFN-α/β by pDCs and the IFN-α/β “signature” often seen in human lupus patients. The specific contributio...

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Detalles Bibliográficos
Autores principales: Rowland, Sarah L., Riggs, Jeffrey M., Gilfillan, Susan, Bugatti, Mattia, Vermi, William, Kolbeck, Roland, Unanue, Emil R., Sanjuan, Miguel A., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172228/
https://www.ncbi.nlm.nih.gov/pubmed/25180065
http://dx.doi.org/10.1084/jem.20132620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172228/
https://www.ncbi.nlm.nih.gov/pubmed/25180065
http://dx.doi.org/10.1084/jem.20132620

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