Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Al...

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Detalles Bibliográficos
Autores principales: Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172285/
https://www.ncbi.nlm.nih.gov/pubmed/25258700
http://dx.doi.org/10.4172/2161-0460.S10-007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172285/
https://www.ncbi.nlm.nih.gov/pubmed/25258700
http://dx.doi.org/10.4172/2161-0460.S10-007

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