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Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention
Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Al...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172285/ https://www.ncbi.nlm.nih.gov/pubmed/25258700 http://dx.doi.org/10.4172/2161-0460.S10-007 |