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RGDechi-hCit: αvβ3 Selective Pro-Apoptotic Peptide as Potential Carrier for Drug Delivery into Melanoma Metastatic Cells

αvβ3 integrin is an important tumor marker widely expressed on the surface of cancer cells. Recently, we reported some biological features of RGDechi-hCit, an αvβ3 selective peptide antagonist. In the present work, we mainly investigated the pro-apoptotic activity of the molecule and its ability to...

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Detalles Bibliográficos
Autores principales: Capasso, Domenica, de Paola, Ivan, Liguoro, Annamaria, Del Gatto, Annarita, Di Gaetano, Sonia, Guarnieri, Daniela, Saviano, Michele, Zaccaro, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172472/
https://www.ncbi.nlm.nih.gov/pubmed/25248000
http://dx.doi.org/10.1371/journal.pone.0106441